Incyte (INCY) expects to report GAAP (generally accepted accounting principles) and non-GAAP revenues in the range of $80 million to $85 million from the sale of Iclusig in fiscal 2018. In June 2016, Incyte entered a licensing agreement with Ariad Pharmaceuticals for the development and commercialization of kinase inhibitor, Iclusig, in the European Union and 22 other countries. Ariad Pharmaceuticals sold all of its European operations to Incyte in June 2016.
Iclusig is approved in Europe as a treatment option for adults suffering from either chronic phase, accelerated phase, or blast phase chronic myeloid leukemia (or CML), are resistant or intolerant to treatment with Bristol-Myers Squibb’s (BMY) Sprycel (dasatinib) and Novartis’s (NVS) Tasigna (nilotinib), who are not clinically eligible for treatment with Novartis’s Gleevec (imatinib), or who have the T315I mutation. Additionally, Iclusig is also approved for adults suffering from Philadelphia-chromosome positive acute lymphoblastic leukemia (or Ph+ ALL) and who are intolerant or resistant to Sprycel (dasatinib), not clinically eligible for treatment with Gleevec, or have a T315I mutation.
Royalties for Jakavi
In November 2009, Incyte entered a collaboration with Novartis and out-licensed the development and commercialization rights for Jakafi in all hematology and oncology indications in international markets in exchange for milestone payments and royalties. Incyte, however, has retained rights related to the topical formulation of Jakafi. Jakafi is marketed under the brand name of Jakavi by Novartis.
In April 2016, Incyte acquired rights from Eli Lilly (LLY) to develop and commercialize Jakafi in graft versus host disease (or GVHD). The company has also amended its agreement and granted exclusive development and commercialization rights to Novartis related to Jakavi in GVHD indication in international markets.
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In the next article, we’ll discuss growth prospects for Olumiant in greater detail.
In January 2015, Incyte (INCY) entered an antibody discovery collaboration with Agenus (AGEN).
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